Fluorescent probe for the peripheral-type benzodiazepine receptor (PBR) (Ex(max): 470nm, Em(max): 530nm). The only available tool for imaging PBRs in cellular systems.
Product Details
| Alternative Name: | N3'-[6-((7-Nitro-2,1,3-benzoxadiol-4-yl)amino)hexyl]2-phenylindole-3-acetamide |
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| Formula: | C28H28N6O4 |
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| MW: | 512.6 |
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| CAS: | 336111-14-9 |
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| Purity: | ≥96% |
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| Appearance: | Red solid. |
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| Solubility: | Soluble in DMSO or 100% ethanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis: E.G. Jorda, et al.; Apoptosis
10, 91 (2005),
Abstract;
Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor: A.P. Kozikowski, et al.; J. Med. Chem.
40, 2435 (1997),
Abstract;
Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: biological role in steroidogenic cell function: V. Papadopoulos; Endocr. Rev.
14, 222 (1993),
Abstract;
