Potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase (NAALADase), which is a membrane-bound peptidase that hydrolyses N-acetyl-L-aspartate-L-glutamate (NAAG) (Prod. No. ALX-151-020), a major brain peptide.
Product Details
| Alternative Name: | PMPA |
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| Formula: | C6H11O7P |
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| MW: | 226.1 |
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| CAS: | 173039-10-6 |
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| Purity: | ≥97% (HPLC) |
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| Identity: | Determined by NMR. |
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| Appearance: | Viscous, colorless oil. |
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| Solubility: | Soluble in water, methanol or DMSO. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II: R. Luthi-Carter, et al.; Brain Res.
795, 341 (1998),
Abstract;
Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase: P.F. Jackson, et al.; J. Med. Chem.
39, 619 (1996),
Abstract;
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