ATP analog that can substitute ATP in various kinase reactions. Substrate and inhibitor of ATP-dependent enzyme systems. The resulting thiophosphorylated proteins are resistant to dephosphorylation by protein phosphatases. Increases the activity of Ca2 -activated K channels.
Product Details
| Alternative Name: | ATP-γS . 4Li |
| |
| Formula: | C10H12N5O12P3S . 4Li |
| |
| MW: | 547 |
| |
| CAS: | 93839-89-5 |
| |
| Purity: | ≥90% (HPLC) |
| |
| Appearance: | White to off-white solid. |
| |
| Solubility: | Soluble in water. |
| |
| Shipping: | Shipped on Blue Ice |
| |
| Long Term Storage: | -20°C |
| |
| Use/Stability: | Stock solutions may be stored at -80°C for up to 1 month. Product is not sterile. |
| |
| Handling: | Protect from moisture. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Regulation of TRPV1 channel activities by intracellular ATP in the absence of capsaicin: T. Shimizu, et al.; Biochim. Biophys. Acta Biomembr.
1864, 183782 (2021),
Abstract;
Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation: J. Chen, et al.; Science
257, 1261 (1992),
Abstract;
Regulation of phosphoinositide breakdown by guanine nucleotides: I. Litosch & J.N. Fain; Life Sci.
39, 187 (1986),
Abstract;
The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate): S. Chrysogelos, et al.; J. Biol. Chem.
258, 12624 (1983),
Abstract;
Full Text
