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Apoptosis Activator 2

Apoptosis inducer
 
ALX-420-035-M005 5 mg 37.00 USD
 
ALX-420-035-M025 25 mg 148.00 USD
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Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome, triggering caspase-9 activation resulting in activated caspase-3. Shows strong selectivity for cancer cells against normal cell lines. Acts in a similar way like apoptosis inducer PETCM (Prod. No. ALX-420-031).

Product Specification

Alternative Name:1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione
 
Formula:C15H9NO2Cl2
 
MW:306.1
 
CAS:79183-19-0
 
Purity:≥98% (HPLC)
 
Appearance:Orange to red solid.
 
MeltingPoint:174-175°C
 
Solubility:Soluble in DMSO (5mg/ml), methanol (5mg/ml) or 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Regulatory Status:RUO - Research Use Only
 
420-035
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420-035

Product Literature References

Direct activation of the apoptosis machinery as a mechanism to target cancer cells: J.T. Nguyen and J.A. Wells; PNAS 100, 7533 (2003), Abstract; Full Text

Related Products

PETCM 

Caspase-3 activator
10129-56-3, ≥95% | Print as PDF
 
ALX-420-031-M010 10 mg 51.00 USD
 
ALX-420-031-M050 50 mg 250.00 USD
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