Antiviral agent. Antioxidant. Antitumor compound. Apoptosis inducer.
Product Details
Alternative Name: | 3-Methylquercetin, 3'-Methoxy-3,4',5,7-tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone |
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Formula: | C16H12O7 |
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MW: | 316.3 |
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CAS: | 480-19-3 |
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Purity: | ≥98% (HPLC) |
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Identity: | Determined by NMR and MS. |
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Appearance: | Yellow crystalline solid. |
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Solubility: | Soluble in acetone, methanol, ethylacetate or DMSO. Only sparingly soluble in water. |
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Shipping: | Ambient |
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Long Term Storage: | +4°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells: G. Ma, et al.; Chem. Biol. Interact.
167, 153 (2007),
Abstract;
Isorhamnetin prevent endothelial cell injuries from oxidized LDL via activation of p38MAPK: M. Bao & Y. Lou; Eur. J. Pharmacol.
547, 22 (2006),
Abstract;
Antioxidant effects of isorhamnetin 3,7-di-O-beta-D-glucopyranoside isolated from mustard leaf (Brassica juncea) in rats with streptozotocin-induced diabetes: T. Yokozawa, et al.; J. Agric. Food Chem.
50, 5490 (2002),
Abstract;
Effect of five flavonoid compounds isolated from leaves of Diospyros kaki on stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils: G. Chen, et al.; Clin. Chim. Acta
326, 169 (2002),
Abstract;
Effects of intrinsic fluorescence and quenching on fluorescence-based screening of natural products: L. Zou, et al.; Phytomedicine
9, 263 (2002),
Abstract;
Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima: H. Ito, et al.; Cancer Lett.
143, 5 (1999),
Abstract;
Inhibition of xanthine oxidase by flavonoids: A. Nagao, et al.; Biosci. Biotechnol. Biochem.
63, 1787 (1999),
Abstract;