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Isorhamnetin

Antitumor agent
 
ALX-385-024-M005 5 mg 117.00 USD
 
ALX-385-024-M010 10 mg 197.00 USD
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Antiviral agent. Antioxidant. Antitumor compound. Apoptosis inducer.

Product Specification

Alternative Name:3-Methylquercetin, 3'-Methoxy-3,4',5,7-tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone
 
Formula:C16H12O7
 
MW:316.3
 
CAS:480-19-3
 
Purity:≥98% (HPLC)
 
Identity:Determined by NMR and MS.
 
Appearance:Yellow crystalline solid.
 
Solubility:Soluble in acetone, methanol, ethylacetate or DMSO. Only sparingly soluble in water.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Regulatory Status:RUO - Research Use Only
 
385-024
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385-024

Product Literature References

The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells: G. Ma, et al.; Chem. Biol. Interact. 167, 153 (2007), Abstract;
Isorhamnetin prevent endothelial cell injuries from oxidized LDL via activation of p38MAPK: M. Bao & Y. Lou; Eur. J. Pharmacol. 547, 22 (2006), Abstract;
Antioxidant effects of isorhamnetin 3,7-di-O-beta-D-glucopyranoside isolated from mustard leaf (Brassica juncea) in rats with streptozotocin-induced diabetes: T. Yokozawa, et al.; J. Agric. Food Chem. 50, 5490 (2002), Abstract;
Effect of five flavonoid compounds isolated from leaves of Diospyros kaki on stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils: G. Chen, et al.; Clin. Chim. Acta 326, 169 (2002), Abstract;
Effects of intrinsic fluorescence and quenching on fluorescence-based screening of natural products: L. Zou, et al.; Phytomedicine 9, 263 (2002), Abstract;
Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima: H. Ito, et al.; Cancer Lett. 143, 5 (1999), Abstract;
Inhibition of xanthine oxidase by flavonoids: A. Nagao, et al.; Biosci. Biotechnol. Biochem. 63, 1787 (1999), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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