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ALX-380-274-G005 5 g 70.00 USD
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Macrolide antibiotic. Inhibits protein synthesis (elongation) at the transpeptidation step. Binds to the 23S RNA of the 50S ribosomal subunit. Effective against Gram-negative and Gram-positive bacteria.

Product Details

Source:Isolated from Streptomyces erythreus.
MI:14: 3681
Purity:≥85% (Assay on dry basis)
Appearance:White to off-white powder.
Solubility:Soluble in water (50mg/ml), 100% ethanol or methanol.
Shipping:Ambient Temperature
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Inhibition of the metabolism of brotizolam by erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in brotizolam metabolism: T. Tokairin, et al.; Br. J. Clin. Pharmacol. 60, 172 (2005), Abstract; Full Text
Assessment of the potential pharmacokinetic and pharmacodynamic interactions between erythromycin and argatroban: J.Q. Tran, et al.; J. Clin. Pharmacol. 39, 513 (1999), Abstract;
Erythromycin inhibits transcriptional activation of NF-kappaB, but not NFAT, through calcineurin-independent signaling in T cells: Y. Aoki & P.N. Kao; Antimicrob. Agents Chemother. 43, 2678 (1999), Abstract; Full Text
Inducible erythromycin resistance in bacteria: B. Weisblum; Br. Med. Bull. 40, 47 (1984), Abstract;