Antibiotic. Potent inhibitor of protein kinase C (PKC). Inhibits the cell cycle at the G2 stage.
Product Details
Alternative Name: | Antibiotic BMY 41950, Antibiotic RK 1409, LCM76-L |
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Formula: | C28H24N4O4 |
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MW: | 480.5 |
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Source: | Isolated from Streptomyces sp. MST-AS5345. |
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CAS: | 125035-83-8 |
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Purity: | ≥98% (HPLC) |
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Appearance: | Yellow solid. |
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Solubility: | Soluble in DMSO, dimethyl formamide, methanol or 100% ethanol; slightly soluble in water. |
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Shipping: | Ambient |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). I. Taxonomy and biological activity: H. Osada, et al.; J. Antibiot.
45, 189 (1992),
Abstract;
A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). II. Fermentation, isolation, physico-chemical properties and structure: H. Koshino, et al.; J. Antibiot.
45, 195 (1992),
Abstract;