- Antimycin A complex composed mostly of Antimycin A1, A2, A3, and A4
- Used for the study of the mitochondrial function
Antimycin A is a bacterial metabolite complex produced by Streptomyces. It is composed majorly of Antimycin A1, A2, A3, and A4. Antimycin A is an antibiotic. It is capable of inducing apoptosis in mammalian cells, which is not prevented by the presence of Bcl-2. Antimycin A acts as an inhibitor of cellular respiration and more specifically, the electron transport chain of oxidative phosphorylation via its binding to cytochrome c reductase.
Product Details
| Alternative Name: | Antipiricullin, Virosin |
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| Source: | Isolated from Streptomyces sp. Mixture of antimycin A's. |
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| CAS: | 1397-94-0 |
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| MI: | 14: 714 (A1) & 715 (A3) |
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| RTECS: | CD0350000 |
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| Identity: | Identity determined by NMR. |
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| Appearance: | White to faint yellow powder. |
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| Solubility: | Soluble in 100% ethanol (50mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Application(s): Inhibitor of complex III in the electron transport chain,
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