Antibacterial and anti-inflammatory compound. Apoptosis inducer.
Product Details
Formula: | C15H22O |
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MW: | 218.3 |
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Source: | Synthetic. |
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CAS: | 30199-26-9 |
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Purity: | ≥97% (HPLC) |
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Identity: | Identity determined by 1H-NMR, 13C-NMR and MS. |
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Appearance: | Colorless to light yellow oil. |
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Solubility: | Soluble in DMSO or 100% ethanol. |
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Shipping: | Ambient |
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Long Term Storage: | -20°C |
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Handling: | Protect from light. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Regulation of p53-, Bcl-2- and caspase-dependent signaling pathway in xanthorrhizol-induced apoptosis of HepG2 hepatoma cells: T. Handayani, et al.; Anticancer Res.
27, 965 (2007),
Abstract;
Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B: W.Y. Chung, et al.; Carcinogenesis
28, 1224 (2007),
Abstract;
Xanthorrhizol induces apoptosis via the up-regulation of bax and p53 in HeLa cells: N. Ismail, et al.; Anticancer Res.
25, 2221 (2005),
Abstract;
Xanthorrhizol: a potential antibacterial agent from Curcuma xanthorrhiza against Streptococcus mutans: J.K. Hwang, et al.; Planta Med.
66, 196 (2000),
Abstract;
Effect of xanthorrhizol, xanthorrhizol glycoside and trachylobanoic acid isolated from Cachani complex plants upon the contractile activity of uterine smooth muscle: H. Ponce-Monter, et al.; Phytother. Res.
13, 202 (1999),
Abstract;