Induces phase II detoxifying enzymes and inhibits chemically induced carcinogenesis. Exhibits immunomodulatory activity and also inhibits HIV-1 replication. Does not possess any inherent antioxidant capacity.
Product Details
| Formula: | C28H34O9 |
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| MW: | 514.6 |
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| Source: | Isolated from grapefruit seed and citrus juice. |
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| CAS: | 1063-77-0 |
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| MI: | 14: 6674 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in acetone; slightly soluble in 100% ethanol, methanol, isopropanol or ethyl acetate; insoluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside: A.P. Breksa, 3rd & G.D. Manners; J. Agric. Food Chem.
54, 3827 (2006),
Abstract;
Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells: L. Battinelli, et al.; Planta Med.
69, 910 (2003),
Abstract;
Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune system: T.J. Raphael & G. Kuttan; Phytomedicine
10, 483 (2003),
Abstract;
Inhibition of benzo[a]pyrene-induced forestomach neoplasia in mice by citrus limonoids: L.K.T. Lam & S. Hasegawa; Nutr. Cancer
12, 43 (1989),
Abstract;
The effect of citrus limonoids on hamster buccal pouch carcinogenesis: E.G. Miller, et al.; Carcinogenesis
10, 1535 (1989),
Abstract;
Limonin and limonoids: chemistry, biochemistry, and juice bitterness: V.P. Maier, et al.; ACS Symposium Series
143, 63 (1980),
Abstract;
