Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=800nM) by binding to the mitotic kinesin Eg5.
Product Details
| Formula: | C23H23N3O3 |
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| MW: | 389.5 |
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| CAS: | 462630-41-7 |
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| Purity: | ≥95% |
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| Identity: | Identity determined by MS, 1H- and 13C-NMR. |
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| Appearance: | Yellow to ocher solid. |
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| Solubility: | Soluble in DMSO (10mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
HR22C16: A Potent Small-Molecule Probe for the Dynamics of Cell Division: S. Hotha, et al.; Angew. Chem. Int. Ed. Engl.
42, 2379 (2003),
Abstract;
