Inhibitor of protein kinases. EGF receptor tyrosine kinase (IC50=7.87µM), PKA (IC50=9.33µM), PKC (IC50=25.01µM). Antioxidant. Antimalarial agent.
Product Details
| Alternative Name: | 7,8-Dihydroxycoumarin |
| |
| Formula: | C9H6O4 |
| |
| MW: | 178.1 |
| |
| CAS: | 486-35-1 |
| |
| RTECS: | GN6382600 |
| |
| Purity: | ≥97% (HPLC) |
| |
| Identity: | Determined by NMR. |
| |
| Appearance: | White to rose powder. |
| |
| Solubility: | Soluble in 100% ethanol, methanol or dimethyl formamide. |
| |
| Shipping: | Ambient |
| |
| Long Term Storage: | Ambient |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Daphnetin, one of coumarin derivatives, is a protein kinase inhibitor: E.B. Yang, et al.; BBRC
260, 682 (1999),
Abstract;
Daphnetin: a novel antimalarial agent with in vitro and in vivo activity: Y.Z. Yang, et al.; Am. J. Trop. Med. Hyg.
46, 15 (1992),
Abstract;
