Inhibitor of protein kinases. EGF receptor tyrosine kinase (IC50=7.87µM), PKA (IC50=9.33µM), PKC (IC50=25.01µM). Antioxidant. Antimalarial agent.
Product Details
| Alternative Name: | 7,8-Dihydroxycoumarin |
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| Formula: | C9H6O4 |
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| MW: | 178.1 |
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| CAS: | 486-35-1 |
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| RTECS: | GN6382600 |
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| Purity: | ≥97% (HPLC) |
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| Identity: | Determined by NMR. |
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| Appearance: | White to rose powder. |
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| Solubility: | Soluble in 100% ethanol, methanol or dimethyl formamide. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Daphnetin, one of coumarin derivatives, is a protein kinase inhibitor: E.B. Yang, et al.; BBRC
260, 682 (1999),
Abstract;
Daphnetin: a novel antimalarial agent with in vitro and in vivo activity: Y.Z. Yang, et al.; Am. J. Trop. Med. Hyg.
46, 15 (1992),
Abstract;
