Product Details
| Alternative Name: | Ang-1, ANGPT1 |
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| MW: | ~55.6kDa |
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| Source: | Produced in E. coli. Human Ang-1 (angiopoietin-1) is a single, non-glycosylated polypeptide chain containing 480 amino acids (20-498) |
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| UniProt ID: | Q15389 |
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| Concentration: | ~1mg/ml |
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| Formulation: | Liquid. Sterile filtered, in 20mM TRIS-HCl buffer, pH 8.0, 1M urea containing 5% glycerol. |
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| Purity: | ≥85% (SDS-PAGE) |
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| Appearance: | Colorless liquid. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store at +4°C if entire vial will be used within 2-4 weeks. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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| Scientific Background: | ANGPT1 is an angiogenic factor which intervenes in blood vessel maturation and takes part in endothelial development. ANGPT1 is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. The glycosylated ANGPT1 protein has a coiled-coil region in the amino terminus and a fibrinogen-like domain at the carboxy terminus. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Dachengqi Decoction Attenuates Intestinal Vascular Endothelial Injury in Severe Acute Pancreatitis in Vitro and in Vivo: L. Y. Pan, et al.; Cell. Physiol. Biochem.
44, 2395 (2017),
Abstract;
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