Product Details
| Sequence: | H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
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| Formula: | C203H311N55O60S |
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| MW: | 4514.1 |
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| CAS: | 107761-42-2 |
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| Quantity: | *Sold as net peptide weight. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White to off-white lyophilized powder. |
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| Solubility: | Soluble in 5% acetic acid. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Technical Info/Product Notes: | Application Note:
Analysis of the Effect of Aggregated β-Amyloid on Cellular Signaling Pathways Critical for Memory in Alzheimer’s disease |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease: L. Gallwitz, et al.; Neurobiol. Dis.
175, 105919 (2022),
Abstract;
Clausena Harmandiana root extract attenuated cognitive impairments via reducing amyloid accumulation and neuroinflammation in Aβ1-42-induced rats: N. Nillert, et al.; BMC Complement Med. Ther.
22, 108 (2022),
Abstract;
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models: M.C. Silva, et al.; Elife
8, e45457 (2019),
Abstract;
Full Text
Heptamer Peptide Disassembles Native Amyloid in Human Plasma Through Heat Shock Protein 70: T.J. Cunningham, et al.; Rejuvenation Res.
21, 527 (2018),
Abstract;
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease: J. Murrell, et al.; Science
254, 97 (1991),
Abstract;
Solution structures of beta peptide and its constituent fragments: relation to amyloid deposition: C.J. Barrow & M.G. Zagorski; Science
253, 179 (1991),
Abstract;
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease: D. Goldgaber, et al.; Science
235, 877 (1987),
Abstract;
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor: J. Kang, et al.; Nature
325, 733 (1987),
Abstract;
