| ADI-KAP-TF022-C | 25 µg | 184.00 USD |  |
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| Alternative Name: | Signal transducer and activator of transcription 3 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human Stat3 phosphorylated at Tyr705. |
| UniProt ID: | P40763 |
| Gene/Protein Identifier: | NP_644805.1 (RefSeq) |
| Source: | Purified from rabbit serum. |
| Species reactivity: | Human |
| Crossreactivity: | Weakly cross-reacts with mouse, rat, bovine and pig Stat3. |
| Applications: | WB |
| Recommended Dilutions/Conditions: | Western Blot (1µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes. |
| Regulatory Status: | RUO - Research Use Only |
