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SARM polyclonal antibody

ADI-CSA-509-E 100 µg 471.00 USD
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Product Details

Alternative Name:TIR-1, Sterile α and TIR motif-containing protein 1, SAM and ARM-containing protein, Sterile α motif and armadillo repeat-containing protein
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human SARM.
UniProt ID:Q6SZW1
Gene/Protein Identifier:NP_055892 (RefSeq)
Species reactivity:Human, Mouse
Applications:ICC, WB
Recommended Dilutions/Conditions:Immunocytochemistry (2µg/ml)
Western Blot (0.5-2.0µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Ion exchange purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Scientific Background:SARM (SAM and ARM-containing protein) is thought to serve as an adaptor protein for the Toll-like receptors (TLRs) and allow for the activation of downstream kinases and NF-κB, ultimately leading to the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.
Regulatory Status:RUO - Research Use Only
SARM polyclonal antibody Western blot
Western blot analysis of SARM in Daudi cell lysates with SARM antibody at (A) 0.5, (B) 1, and (C) 2µg/ml.
SARM polyclonal antibody Immunocytochemistry
Immunocytochemistry analysis of Daudi cells using SARM antibody at 2µg/ml.
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SARM polyclonal antibody Western blot SARM polyclonal antibody Immunocytochemistry

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