Clone: | 1B2F2 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Recombinant human LSD1 truncated protein. |
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UniProt ID: | O60341 |
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Source: | Purified from mouse ascites. |
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Species reactivity: | Human, Mouse, Rat
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Applications: | WB
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Purity Detail: | Protein G affinity purified. |
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Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Lysine-specific demethylase 1 (LSD1, AOF2, BHC110) is a nuclear amine oxidase homolog, and was the first such protein to display definitive activity in epigenetic modulation as a histone demethylase. LSD1 demethylates histone H3 at mono- or di-methylated lysine residues. Depending on associated co-factors, LSD1-mediated demethylation can lead to transcriptional repression or activation. |
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Regulatory Status: | RUO - Research Use Only |
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