| ADI-905-306-100 | 100 µg | 492.00 USD |  |
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| Alternative Name: | B cell maturation protein, TNFRSF 17, CD269 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human BCMA. |
| UniProt ID: | Q02223 |
| Species reactivity: | Human |
| Applications: | ELISA, IF, IHC (PS), WB |
| Recommended Dilutions/Conditions: | Immunofluorescence (20µg/ml) Immunohistochemistry (paraffin sections, 10µg/ml) Western Blot (2-5µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~25kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Use/Stability: | Stable at -20°C up to 1 year, at 4°C up to 3 months. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | -20°C |
| Scientific Background: | Members of the TNF superfamily regulate immune responses and induce apoptosis. Two members of this family were identified and designated BAFF and April, respectively. Three receptors for BAFF were identified; these include: BCMA (B-cell maturation protein), TACI, and BAFF-R. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B-Cell development and survival, activate NF-κB and c-jun N-terminal kinase, and are involved in B-Cell associated autoimmune diseases. |
| Regulatory Status: | RUO - Research Use Only |
