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LVV Hemorphin 7 ELISA kit

Most sensitive and rapid LVV Hemorphin 7 kit for neuroscience market.
ADI-900-205 96 wells 500.00 USD
Do you need bulk/larger quantities?
  • Sensitive - reliably measure as little as 6.1pg/ml of LVV Hemorphin 7
  • Rapid - results in just 3 hours from up to 40 samples in duplicate
  • Specific - low cross-reactivity to similar peptides
  • Easy-to-use - liquid color-coded reagents reduce errors
The LVV Hemorphin 7 EIA kit is a colorimetric, competitive immunoassay kit with results in just 3 hours.
LVV Hemorphin 7 ELISA kit Parallelism curve
LVV Hemorphin 7 ELISA kit Standard curve
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LVV Hemorphin 7 ELISA kit Parallelism curve LVV Hemorphin 7 ELISA kit Standard curve

Product Details

Sensitivity:6.1 pg/ml (range 9.8 - 10,000 pg/ml)
Assay Time:3 hours
Applications:ELISA, Colorimetric detection
Application Notes:For the quantitative determination of species independent LVV Hemorphin 7 in serum and tissue homogenate samples.
Wavelength:450 nm
Species reactivity:Species independent
Crossreactivity:LVV Hemorphin 7 (100%) and <0.003%: Leu-Valorphin-Arg (LVV Hemorphin-6), Valorphin, Angiotensin (1-12), Angiotensin I, Angiotensin (1-9), Angiotensin II, Angiotensin (1-7), Angiotensin A, Angiotensin III, Angiotensin IV
Use/Stability:Store all components at +4ºC, except Standard at -20ºC.
Shipping:Blue Ice
Long Term Storage:-20°C
Contents:Microtiter Plate, Conjugate, Antibody, Assay Buffer 16, Wash Buffer Concentrate, Standard, TMB Substrate, Stop Solution 2, Streptavidin-HRP
Scientific Background:Hemorphins are opioid peptides derived by proteolysis from hemoglobin. Their sequences are identical in several mammalian species including human, sheep and bovine. LVV hemorphin 7 (LVVYPWTQRF) binds strongly to the Angiotensin IV (AT4) receptors in the brain. The AT4 receptor is an integral membrane aminopeptidase also known as IRAP (insulin regulated membrane aminopeptidase). LVV hemorphin 7 and AT4 are not substrates but rather inhibitors of the AT4 (IRAP) receptor. Both promote learning and memory and reverse amnesia in animal models. Elevated serum levels of LVV Hemorphin 7 have also been documented in patients with some forms of breast cancers that are associated with an increased expression of cathespins B and D.
Regulatory Status:RUO - Research Use Only
Compatibility:This product is compatible with the Absorbance 96 Plate Reader.

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Product Literature References

High-dose ferric citrate supplementation attenuates omega-3 polyunsaturated fatty acid biosynthesis via downregulating delta 5 and 6 desaturases in rats with high-fat diet-induced obesity: A. Faradina, et al.; Food Funct. 18, 11819 (2021), Abstract;

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