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PLX4720

Potent and selective B-Raf V600E inhibitor



ENZ-CHM159-0005	5 mg	Inquire for pricing
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Equally potent to c-Raf-1 (Y340D and Y341D mutations), and shows 10-fold selectivity for B-Raf V600E over wild-type B-Raf.

Alternative Name:	N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide

Formula:	C₁₇H₁₄ClF₂N₃O₃S

MW:	413.8

CAS:	918505-84-7

Purity:	≥99% (HPLC)

Identity:	Determined by EM-MS, NMR

Appearance:	Beige powder.

Solubility:	Soluble in DMSO (83mg/ml) or ethanol (1mg/ml).

Shipping:	Ambient Temperature

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only