| Alternative Name: | PYY, peptide tyrosine-tyrosine amide |
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| Clone: | 4 |
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| Host: | Mouse |
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| Isotype: | IgG2aκ |
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| Immunogen: | Synthetic peptide corresponding to aa 3-36 of human Peptide YY coupled to carrier. |
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| UniProt ID: | P10082 |
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| Species reactivity: | Human
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| Applications: | ELISA, WB
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| Application Notes: | Detects a band of ~4kDa by Western blot. |
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| Purity Detail: | Protein A/G-affinity purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Scientific Background: | Peptide tyrosine-tyrosine (PYY) amide is a 36 amino-acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides, and inhibits gall bladder secretion, gut motility and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1. |
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| Regulatory Status: | RUO - Research Use Only |
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