| Alternative Name: | PP |
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| Clone: | 6 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Synthetic human Pancreatic Polypeptide. |
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| UniProt ID: | P01298 |
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| Species reactivity: | Human
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| Applications: | ELISA
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| Application Notes: | Detects a band of ~4kDa by Western blot. |
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| Purity Detail: | Protein A/G-affinity purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Scientific Background: | Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide, with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors. |
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| Regulatory Status: | RUO - Research Use Only |
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