Replaces Prod. #: ALX-550-388
A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.
Product Details
| Formula: | C16H14NO2Cl |
| |
| MW: | 287.8 |
| |
| CAS: | 472981-92-3 |
| |
| Purity: | ≥98% (TLC) |
| |
| Appearance: | Beige solid. |
| |
| MeltingPoint: | 165-167°C |
| |
| Solubility: | Soluble in DMSO (25mg/ml) or 100% ethanol (10mg/ml with warming). |
| |
| Shipping: | Ambient Temperature |
| |
| Long Term Storage: | Ambient |
| |
| Use/Stability: | Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
TRPV1, ASICs and P2X2/3 expressed in bone cells simultaneously regulate bone metabolic markers in ovariectomized mice: K. Kanaya, et al.; J. Musculolskelet. Neuronal Interact.
16, 145 (2016),
Abstract;
Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in the rat: A. Varga, et al.; Neurosci. Lett.
385, 137 (2005),
Abstract;
Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist: M.J. Gunthorpe, et al.; Neuropharmacology
46, 133 (2004),
Abstract;
Identification of SB-366791, a potent and selective antagonist of vanilloid receptor-1: H.K. Rami, et al.; Drugs Fut. 27 (Supply A), 411 (2002),
