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E-64-C

Calpain and cathepsin inhibitor
 
BML-PI106-0005 5 mg 373.00 USD
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Cell-impermeable epoxysuccinyl peptide inhibitor of calpain and other cysteine proteases. Inhibits calpain and cathepsins B, H, and L.

Product Details

Alternative Name:2S,3S-trans-(Carboxyoxirane-2-carbonyl) -L-leucine-(3-methylbutyl) amide
 
MW:314.4
 
Source:Synthetic.
 
CAS:76684-89-4
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white solid
 
Solubility:Soluble in DMSO (5mg/ml).
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 
BML-PI106 structure
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BML-PI106 structure

Product Literature References

A leptospiral AAA+ chaperone-Ntn peptidase complex, HslUV, contributes to the intracellular survival of Leptospira interrogans in hosts and the transmission of leptospirosis: S.L. Dong, et al.; Emerg. Microbes Infect. 6, e105 (2017), Abstract; Full Text

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