Cell-impermeable epoxysuccinyl peptide inhibitor of calpain and other cysteine proteases. Inhibits calpain and cathepsins B, H, and L.
Product Details
Alternative Name: | 2S,3S-trans-(Carboxyoxirane-2-carbonyl) -L-leucine-(3-methylbutyl) amide |
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MW: | 314.4 |
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Source: | Synthetic. |
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CAS: | 76684-89-4 |
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Purity: | ≥98% (HPLC) |
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Appearance: | White to off-white solid |
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Solubility: | Soluble in DMSO (5mg/ml). |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A leptospiral AAA+ chaperone-Ntn peptidase complex, HslUV, contributes to the intracellular survival of Leptospira interrogans in hosts and the transmission of leptospirosis: S.L. Dong, et al.; Emerg. Microbes Infect.
6, e105 (2017),
Abstract;
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