Replaces Prod. #: ALX-270-116
Selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III, IC50=0.6µM).
Product Details
| Alternative Name: | Ro 13-6438, (R)-6-Chloro-1,5-dihydro-3-methyl- imidazo[2,1-b]quinazolin-2-one |
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| Formula: | C11H10ClN3O |
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| MW: | 235.7 |
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| CAS: | 70018-51-8 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in DMSO (3mg/ml) or 100% ethanol (1mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Stable for at least 1 year after receipt when stored at +20°C. Stock solutions are stable for up to 3 months at -20°C. |
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| Technical Info/Product Notes: | Note: Product is not sterile. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties: M. Holck, et al.; J. Cardiovasc. Pharmacol.
6, 520 (1984),
Abstract;
