Fluorogenic substrate for ubiquitin C-terminal hydrolases (UCHs), including UCH-L3 and Isopeptidase T. Sequence is based on the C-terminal residues of ubiquitin. Ex.: 380 nm Em.: 460 nm.
Product Details
| Alternative Name: | Z-LRGG-AMC, Ubiquitin C-terminal hydrolase substrate (fluorogenic), UCH substrate (fluorogenic) |
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| Sequence: | Z-Leu-Arg-Gly-Gly-AMC (7-amino-4-methylcoumarin) |
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| MW: | 692.8 |
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| Purity: | ≥95% |
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| Appearance: | Lyophilized solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells: M. Oroń, et al.; Cell Rep.
40, 111428 (2022),
Abstract;
Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome: K.V. Ramachandran, et al.; Mol. Cell
71, 169 (2018),
Abstract;
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