Sequence is pp60v-src (137-157), which is located in the SH3/SH2 domain region. Non-competitive inhibitor of Src and EGFR. Selectively inhibits protein tyrosine phosphorylation in cell extracts. Peptide is not phosphorylated by Src. IC50=7.5 µM for v-Src. Inhibitory target seems to be a catalytic negative regulatory domain of the tyrosine kinase.
Product Details
| Alternative Name: | pp60v-src (137-157) |
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| Sequence: | Val-Ala-Pro-Ser-Asp-Ser-Ile-Gln-Ala-Glu-Glu-Trp-Tyr-Phe-Gly-Lys-Ile-Thr-Arg-Arg-Glu |
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| MW: | 2482.8 |
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| Purity: | ≥97% |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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