Pseudosubstrate sequence from human PKCζ (113-125) completely conserved in rabbit, rat, mouse and Xenopus. Sequence is also identical in human PKCι; (114-126) and mouse PKCλ. The N-terminus is myristoylated to allow cell permeability. Peptide inhibitor of atypical PKC’s (calcium/phorbol ester/diacyglycerol insensitive). Useful in conjunction with the Myristoylated PKC (20-28), Cell-permeable PKC Inhibitor (BML-P205).
Product Details
| Alternative Name: | Protein kinase C ζ (113-125) (myristoylated), PKCζ pseudosubstrate |
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| Sequence: | N-Myristoyl-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH |
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| Formula: | C90H154N30O17 |
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| MW: | 1928.2 |
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| Formulation: | Lyophilized. |
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| Purity: | ≥97% (HPLC) |
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| Solubility: | Soluble in water or DMSO. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids: A. Khalifeh-Soltani, et al.; Nat. Med.
20, 175 (2014),
Abstract;
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