Competitive inhibitor of PKA (Ki =1.7 nM).
Product Details
| Alternative Name: | cAMP-dependent protein kinase inhibitor (6-22) amide |
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| Sequence: | Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2 |
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| MW: | 1868 |
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| Source: | Synthetic. |
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| CAS: | 121932-06-7 |
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| Formulation: | Lyophilized. Trifluoroacetate salt. |
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| Purity: | ≥97% (HPLC) |
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| Appearance: | Solid. |
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| Solubility: | Soluble in water (10 mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from moisture. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation/Inhibition Balance: Y. Hashimotodani, et al.; Neuron
95, 928 (2017),
Abstract;
Full Text
Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein: D.B. Glass, et al.; J. Biol. Chem.
264, 8802 (1989),
Abstract;
Full Text
