Endogenous agonist for the nuclear receptor LXR.
Product Details
| Formula: | C27H44O2 |
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| MW: | 400.6 |
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| CAS: | 77058-74-3 |
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| Purity: | ≥98% (TLC) |
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| Identity: | Determined by NMR. |
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| Appearance: | White solid. |
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| MeltingPoint: | 156-159°C |
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| Solubility: | Soluble in ethanol (10mg/ml) or DMSO (10mg/ml - requires warming to ~40°C which has been shown to lead to significant decomposition of the product). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Product should be used immediately following dissolution. |
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| Handling: | Store with desiccant. Product packaged under inert gas. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation: J.M. Carthy, et al.; Sci. Rep.
6, 29868 (2016),
Application(s): Screening of chemical compounds with HaCaT cells,
Abstract;
Full Text
Nuclear receptors and lipid physiology: opening the X-files: A. Chawla, et al.; Science
294, 1866 (2001),
Abstract;
