Potent and selective inhibitor of VEGFR-2 (Flk-1, KDR). It displays a 100-fold greater potency for the unactivated form of the kinase (Ki=0.04µM) compared to the activated form (Ki=4µM).
Product Details
| Formula: | C17H16N2O |
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| MW: | 264.3 |
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| CAS: | 5812-07-7 |
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| Purity: | ≥98% |
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| Appearance: | Orange solid. |
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| Solubility: | Soluble in DMSO (25mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation: T.T. Chen, et al.; EBioMedicine
2, 406 (2015),
Application(s): Cell Culture,
Abstract;
