Replaces Prod. #: ALX-480-027
Cell-permeable, phosphodiesterase-resistant cGMP agonist. This analog activates PKA and PKG with similar potency. Much more lipophilic and membrane permeant as compared to cyclic GMP (Prod. No. ALX-480-059) or Sp-cGMPS (Prod. No. ALX-480-073)
Product Details
| Formula: | C10H10BrN5O6PS . Na |
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| MW: | 462.2 |
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| CAS: | 153660-03-8 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | Lyophilized solid. |
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| Solubility: | Soluble in water (25mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Evidence for two intracellular calcium pools in Dictyostelium: the cAMP-induced calcium influx is directed into a NBD-Cl- and 2,5-di-(tert-butyl)1,4-hydroquinone-sensitive pool: H. Flaadt et al.; J. Cell. Sci.
105 ( Pt 4), 1131 (1993),
Abstract;
