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Sterigmatocystin

Mycotoxin
 
ALX-630-116-M001 1 mg 60.00 USD
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Mycotoxin produced by strains of the common molds. Inhibitor of DNA synthesis. Induces sister chromatid exchanges in bone marrow cells of mice. Causes necrosis.

Product Details

Alternative Name:3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furol[3’,2’:4,5]furo[2,3-c]xanthen-7-one
 
Formula:C18H12O6
 
MW:324.3
 
Source:Isolated from Aspergillus versicolor.
 
CAS:10048-13-2
 
RTECS:LV1750000
 
Purity:≥98% (TLC, HPLC)
 
Appearance:Pale yellow solid.
 
Solubility:Soluble in DMSO (10mg/ml), chloroform (71mg/ml), pyridine (18mg/ml) or acetone (5mg/ml).
 
Shipping:Ambient Temperature
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
Regulatory Status:RUO - Research Use Only
 
630-116
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Product Literature References

A novel biosensor for sterigmatocystin constructed by multi-walled carbon nanotubes (MWNT) modified with aflatoxin-detoxifizyme (ADTZ): D.S. Yao, et al.; Bioelectrochemistry 68, 126 (2006), Abstract;
An aflatoxin biosynthesis cluster gene encodes a novel oxidase required for conversion of versicolorin a to sterigmatocystin: K.C. Ehrlich, et al.; Appl. Environ. Microbiol. 71, 8963 (2005), Abstract; Full Text
Aspergillus mycotoxins and their effect on the host: K. Kamei & A. Watanabe; Med. Mycol. 43, S95 (2005), Abstract;
Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bünger, et al.; Toxicology 202, 199 (2004), Abstract;
Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin: P.T. Curry, et al.; Mutat. Res. 137, 111 (1984), Abstract;
Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin: K. Terao; Acta Pathol. Jpn. 23, 647 (1973), Abstract;
Effect of sterigmatocystin on rat liver nuclear RNA: W. Nel & H.E. Pretorius; Biochem. Pharmacol. 19, 957 (1970), Abstract;

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