Mycotoxin produced by strains of the common molds. Inhibitor of DNA synthesis. Induces sister chromatid exchanges in bone marrow cells of mice. Causes necrosis.
Product Details
Alternative Name: | 3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furol[3’,2’:4,5]furo[2,3-c]xanthen-7-one |
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Formula: | C18H12O6 |
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MW: | 324.3 |
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Source: | Isolated from Aspergillus versicolor. |
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CAS: | 10048-13-2 |
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RTECS: | LV1750000 |
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Purity: | ≥98% (TLC, HPLC) |
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Appearance: | Pale yellow solid. |
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Solubility: | Soluble in DMSO (10mg/ml), chloroform (71mg/ml), pyridine (18mg/ml) or acetone (5mg/ml). |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Handling: | Protect from light. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A novel biosensor for sterigmatocystin constructed by multi-walled carbon nanotubes (MWNT) modified with aflatoxin-detoxifizyme (ADTZ): D.S. Yao, et al.; Bioelectrochemistry
68, 126 (2006),
Abstract;
An aflatoxin biosynthesis cluster gene encodes a novel oxidase required for conversion of versicolorin a to sterigmatocystin: K.C. Ehrlich, et al.; Appl. Environ. Microbiol.
71, 8963 (2005),
Abstract;
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Aspergillus mycotoxins and their effect on the host: K. Kamei & A. Watanabe; Med. Mycol.
43, S95 (2005),
Abstract;
Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bünger, et al.; Toxicology
202, 199 (2004),
Abstract;
Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin: P.T. Curry, et al.; Mutat. Res.
137, 111 (1984),
Abstract;
Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin: K. Terao; Acta Pathol. Jpn.
23, 647 (1973),
Abstract;
Effect of sterigmatocystin on rat liver nuclear RNA: W. Nel & H.E. Pretorius; Biochem. Pharmacol.
19, 957 (1970),
Abstract;