GABAA receptor antagonist.
Product Details
Alternative Name: | D-Bicuculline |
|
Formula: | C20H17NO6 |
|
MW: | 367.4 |
|
CAS: | 485-49-4 |
|
MI: | 14: 1203 |
|
RTECS: | LV0909840 |
|
Purity: | ≥98% (HPLC) |
|
Appearance: | Off-white to yellow powder. |
|
Solubility: | Soluble in benzene, chloroform or ethyl acetate. |
|
Shipping: | Ambient Temperature |
|
Long Term Storage: | -20°C |
|
Regulatory Status: | RUO - Research Use Only |
|
Please mouse over
Product Literature References
Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway: X. Wang, et al.; Neurobiol- Aging
121, 64 (2023),
Abstract;
Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition: G. Figlia, et al.; Nat. Cell Biol.
24, 1407 (2022),
Abstract;
Nuclear calcium signaling induces expression of the synaptic organizers lrrtm1 and lrrtm2: S.N. Hayer, et al.; J. Biol. Chem.
290, 5523 (2015),
Application(s): Cell Culture,
Abstract;
Full Text
Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production: Sarah E. Hoey, et al.; J. Neurosci.
29, 4442 (2009),
Abstract;
Convulsant bicuculline modifies CNS muscarinic receptor affinity: P.G. Schneider and G. Rodriguez de Lores Arnaiz; BMC Neurosci.
7, 32 (2006),
Abstract;
Full Text
Cannabinoid suppressed bicuculline-induced convulsion without respiratory depression in the brainstem-spinal cord preparation from newborn rats: S. Koda, et al.; Biomed. Res.
26, 241 (2005),
Abstract;
Full Text