Inhibitor of the K+/Cl--cotransport that does not affect the bumetanide-sensitive Na+/K+/Cl--cotransport system.
Product Details
| Alternative Name: | R-(+)-Butylindazone, (Dihydroindenyl)oxy alkanoic acid |
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| Formula: | C20H24Cl2O4 |
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| MW: | 399.3 |
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| CAS: | 81166-47-4 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White solid. |
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| Solubility: | Soluble in 100% ethanol or dilute aqueous base; insoluble in water or dilute aqueous acid. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive [Na+,K+,Cl- ]-cotransport system: R.P. Garay, et al.; Mol. Pharmacol.
33, 696 (1988),
Abstract;
The significance of the relative effects of loop diuretics and anti-brain edema agents on the Na+,K+,Cl- cotransport system and the Cl-/NaCO3- anion exchanger: R.P. Garay, et al.; Naunyn-Schmiedeberg's Arch. Pharmacol.
334, 202 (1986),
Abstract;
