Fluorescent, highly potent phorbol ester. Useful for membrane studies.
Product Details
| Alternative Name: | Phorbol 12-N-methylanthranilate |
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| Formula: | C30H37NO8 |
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| MW: | 539.6 |
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| CAS: | 80998-07-8 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in methanol, DMSO or chloroform. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Phorbol esters: structure, biological activity, and toxicity in animals: G. Goel, et al.; Int. J. Toxicol.
26, 279 (2007),
Abstract;
Conformation of the C1 phorbol-ester-binding domain participates in the activating conformational change of protein kinase C: C. Ho, et al.; Biochem. J.
344, 451 (1999),
Abstract;
Full Text
Sapintoxin D is a weak tumour promoter in Sencar mouse skin: J.R. McLean, et al.; J. Pharm. Pharmacol.
47, 263 (1995),
Abstract;
Effects of five phorbol esters on gap junctional intercellular communication, morphological transformation and epidermal growth factor binding in Syrian hamster embryo cells: T. Husoy, et al.; Carcinogenesis
14, 73 (1993),
Abstract;
Effects of biologically active tumour-promoting and non-promoting phorbol esters on in vitro growth of melanocytic cells: G. Brooks, et al.; Pigment Cell. Res.
3, 98 (1990),
Abstract;
Fluorescent phorbol ester binding to the receptor protein kinase c in-vitro and in-vivo: N.A. Morrice, et al.; J. Pharm. Pharmacol.
38, 30P (1986),
Abstract;
Sapintoxin D, A New Phorbol Ester From Sapium indicum: S.E. Taylor, et al.; J. Nat. Prod.
44, 729 (1981),
Abstract;
