First molecule to directly activate procaspase-3 to caspase-3 in vitro. Has been shown to induce apoptosis in cancer cells.
Product Details
| Alternative Name: | 4-(Phenylmethyl)[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide-1-piperazine acetic acid |
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| Formula: | C23H28N4O2 |
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| MW: | 392.5 |
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| CAS: | 315183-21-2 |
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| Purity: | ≥98% (HPLC (UV)) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in acetonitrile, DMSO, dioxane or methanol. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy: K.S. Putt, et al.; Nat. Chem. Biol.
2, 543 (2006),
Abstract;
