Anti-obesity agent. Prevents resorption of the messenger substances serotonin and noradrenalin in the brain, allowing them to act at higher concentration on nerve cells and increasing the feeling of satiety.
Product Details
| Alternative Name: | 1-(4-Chlorophenyl-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine . HCl . H2O |
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| Formula: | C17H26ClN . HCl . H2O |
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| MW: | 279.9 . 36.5 . 18.0 |
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| CAS: | 125494-59-9 |
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| MI: | 14: 8485 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white crystalline powder. |
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| MeltingPoint: | 190-201°C |
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| Solubility: | Soluble in methanol or water (2.9mg/ml at pH 5.2). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve: H. Ueno, et al.; PLoS One
14, e0222653 (2019),
Abstract;
SCO-792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice: H.Yashiro, et al.; Diabetes Obes. Metab.
21, 2228 (2019),
Abstract;
A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models: Y. Kawata, et al.; Eur. J. Pharmacol.
796, 45 (2016),
Abstract;
