Phosphodiesterase inhibitor. Blocks the synthesis of TNF-α. Improves blood flow by decreasing blood viscosity.
Product Details
| Alternative Name: | Trental, 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione |
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| Formula: | C13H18N4O3 |
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| MW: | 278.3 |
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| Source: | Isolated from Penicillium expansum. |
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| CAS: | 6493-05-6 |
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| MI: | 14: 7136 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White to off-white crystalline powder. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism: K. Prasad & P. Lee; Atherosclerosis
192, 313 (2007),
Abstract;
Pentoxifylline: C.P. Samlaska & E.A. Winfield; J. Am. Acad. Dermatol.
30, 603 (1994), Review,
Abstract;
Pentoxifylline inhibits the expression of tissue factor mRNA in endotoxin-activated human monocytes: V. Ollivier, et al.; FEBS Lett.
322, 231 (1993),
Abstract;
Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality: P. Noel, et al.; Life Sci.
47, 1023 (1990),
Abstract;
