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OBAA

PLA2 inhibitor
 
ALX-270-105-M005 5 mg 37.00 USD
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Replaces Prod. #: BML-ST315

Potent inhibitor of snake venom PLA2 (IC50=0.7µM). Induces apoptosis in human endothelial cells.

Product Details

Alternative Name:3-(4-Octadecyl)-benzoylacrylic acid, 4-(4-Octadecylphenyl)-4-oxobutenoic acid
 
Formula:C28H44O3
 
MW:428.6
 
CAS:134531-42-3
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (50mg/ml), 100% ethanol (5mg/ml; warm) or methanol.
 
Shipping:Ambient Temperature
 
Long Term Storage:Ambient
 
Regulatory Status:RUO - Research Use Only
 
ALX-270-105
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ALX-270-105

Product Literature References

Phospholipase A2 inhibition by alkylbenzoylacrylic acids: T. Köhler, et al.; Biochem. Pharmacol. 44, 805 (1992), Abstract;
Allergen-induced bronchospasm in passively sensitized guinea pigs: influence of new substances in comparison to reference compounds: S. Madi, et al.; Agents Actions 32, 144 (1991), Abstract;
Phospholipase A2 inhibition by alkylbenzoylacrylic acids: T. Köhler, et al.; Agents Actions 32, 70 (1991), Abstract;

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