Replaces Prod. #: BML-ST315
Potent inhibitor of snake venom PLA2 (IC50=0.7µM). Induces apoptosis in human endothelial cells.
Product Details
Alternative Name: | 3-(4-Octadecyl)-benzoylacrylic acid, 4-(4-Octadecylphenyl)-4-oxobutenoic acid |
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Formula: | C28H44O3 |
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MW: | 428.6 |
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CAS: | 134531-42-3 |
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Purity: | ≥98% (TLC) |
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Appearance: | White solid. |
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Solubility: | Soluble in DMSO (50mg/ml), 100% ethanol (5mg/ml; warm) or methanol. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Phospholipase A2 inhibition by alkylbenzoylacrylic acids: T. Köhler, et al.; Biochem. Pharmacol.
44, 805 (1992),
Abstract;
Allergen-induced bronchospasm in passively sensitized guinea pigs: influence of new substances in comparison to reference compounds: S. Madi, et al.; Agents Actions
32, 144 (1991),
Abstract;
Phospholipase A2 inhibition by alkylbenzoylacrylic acids: T. Köhler, et al.; Agents Actions
32, 70 (1991),
Abstract;