Product Details
| Alternative Name: | Poly(ADP-ribose) polymerase 1 |
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| Source: | Produced in Sf21 insect cells. Human full-length PARP-1 is fused to a Myc-tag and a His-tag. Produced in a baculovirus expression system. |
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| UniProt ID: | P09874 |
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| Formulation: | Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 50mM imidazole, 0.2% NP-40 and 10% glycerol. |
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| Purity: | ≥98% (SDS-PAGE) |
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| Specific Activity: | ≥1’200U/mg protein. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Identification of poly (ADP-ribose) polymerase-1 (PARP-1) as a novel Kruppel-like factor 8-interacting and -regulating protein: H. Lu, et al.; J. Biol. Chem.
286, 20335 (2011),
Abstract;
Full Text
Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription: P.O. Hassa, et al.; J. Biol. Chem.
280, 40450 (2005),
Abstract;
Full Text
Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1: P.O. Hassa, et al.; J. Biol. Chem.
278, 45145 (2003),
Abstract;
Full Text
