The peptide sequence corresponds to amino acid residues 1149-1158 of the guanine nucleotide-releasing factor hSos1, which is essential for the control of Ras activity. Blocks the binding of hSos1 to human Grb2, a protein that binds to activated receptor tyrosine kinases.
Product Details
| Alternative Name: | SOS-1 (human) (1149-1158) |
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| Sequence: | H-Val-Pro-Pro-Pro-Val-Pro-Pro-Arg-Arg-Arg-OH |
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| Formula: | C53H91N19O11 |
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| MW: | 1170.4 |
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| Purity: | ≥97% |
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| Appearance: | White lyophilized powder. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling: N. Li, et al.; Nature
363, 85 (1993),
Abstract;
