Hypothalamic neuropeptide that stimulates food intake in rats with impressive potency. Binds specifically to the OX1 receptor.
Product Details
Sequence: | Glp-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2
(Disulfide bonds between Cys6-Cys12 and Cys7-Cys14). |
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Formula: | C152H243N47O44S4 |
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MW: | 3561.2 |
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Formulation: | Lyophilized. |
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Peptide Content: | 70-90% |
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Purity: | ≥98% (HPLC) |
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Solubility: | Soluble in DMSO; can be diluted with buffers or distilled water. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Orexins and appetite: the big picture of energy homeostasis gets a little bigger: M.W. Schwartz; Nature Medicine
4, 385 (1998),
Abstract;
Orexins and orexin receptors: a family of hypotalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviour: T. Sakurai, et al.; Cell
92, 573 (1998),
Abstract;