Product Details
Alternative Name: | STX13, Syntaxin 12 |
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Clone: | 15G2 |
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Host: | Mouse |
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Isotype: | IgG |
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Immunogen: | Recombinant cytoplasmic domain of rat syntaxin 13. |
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UniProt ID: | G3V7P1 |
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GenBank ID: | AF044581 |
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Source: | Purified from ascites. |
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Species reactivity: | Human, Mouse, Rat Dog, Hamster
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Applications: | IHC (PS), WB
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Recommended Dilutions/Conditions: | Western Blot (1:1,000, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~38kDa by Western blot. |
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Purity Detail: | Protein G affinity purified. |
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Formulation: | Liquid. In PBS containing 50% glycerol and 0.09% sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles. |
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Regulatory Status: | RUO - Research Use Only |
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Western blot analysis of Syntaxin 13 (15G2), mAb (Prod. No. ADI-VAM-SV026): Lane 1: MW Marker, Lane 2: Rat Brain Lysate (Prod. No. ADI-LYT-RB100), Lane 3: Mouse Brain Lysate (Prod. No. ADI-LYT-MB100), Lane 4: CHO-K1 Cell Lysate (Heat Shocked)
Immunohistochemistry analysis of human placenta tissue stained with Syntaxin 13, mAb (15G2) at 20µg/ml.
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Product Literature References
The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency: J. Gitschier, et al. ; Nat. Genet.
23, 329 (1999),
Application(s): WB, ICC using mouse samples,
Abstract;
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