Alternative Name: | TGF-β-activated kinase-1 |
|
Host: | Rabbit |
|
Immunogen: | Synthetic peptide corresponding to a portion of mouse TAK1. |
|
UniProt ID: | Q62073 |
|
GenBank ID: | D76466 |
|
Source: | Purified from rabbit serum. |
|
Species reactivity: | Human, Mouse, Rat Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep, Xenopus
|
|
Applications: | IHC (PS), WB
|
|
Recommended Dilutions/Conditions: | Western Blot (1µg/ml, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
|
Purity Detail: | Protein A affinity purified. |
|
Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
|
Handling: | Avoid freeze/thaw cycles. |
|
Shipping: | Blue Ice |
|
Long Term Storage: | -20°C |
|
Scientific Background: | TAK1 (TGF-beta-activated kinase-1) is a 65 kDa serine/threonine kinase that is a member of the MAPKKK family. TAK1 is involved in the regulation of transcription by the TGF-beta super family, as its kinase activity is stimulated by TGF-beta and bone morphogenetic protein (BMP). |
|
Regulatory Status: | RUO - Research Use Only |
|
IHC Analysis: Human placenta tissue stained with TAK1, pAb at 10µg/ml.
IHC Analysis: Human prostate tissue stained with TAK1, pAb at 10µg/ml.
IHC Analysis: Human tonsil tissue stained with TAK1, pAb at 10µg/ml.