| ADI-KAP-TK140-E | 100 µg | 470.00 USD |  |
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| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human SHPS-1/SIRP-1α. |
| UniProt ID: | P78324 |
| GenBank ID: | D86043 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | ICC, WB |
| Recommended Dilutions/Conditions: | Immunocytochemistry (1µg/ml) Western Blot (0.5-1.0µg/ml, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~80-95kDa by Western blot. |
| Purity Detail: | DEAE purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | SHPS-1 is a member of the gene family called the signal regulatory proteins of which there are at least fifteen members. SHPS-1 is a substrate of many activated tyrosine kinases such as Insulin receptor and EGFR, amongst others. SHPS-1 has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes. |
| Regulatory Status: | RUO - Research Use Only |
