| ADI-KAP-MA003-E | 100 µg | 372.00 USD |  |
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| Alternative Name: | MKK5, MAP kinase kinase 5 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human MEK5. The sequence is completely conserved in rat. |
| UniProt ID: | Q13163 |
| GenBank ID: | U71088 |
| Source: | Purified from rabbit serum. |
| Species reactivity: | Human, Mouse, Rat Dog, Monkey, Rabbit, Sheep, Xenopus |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~42kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS, pH 7.2, containing 0.09% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis. |
| Regulatory Status: | RUO - Research Use Only |
Jurkat, (cell lysate) |
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| Human, WB | Print as PDF | ||||||
| ADI-LYC-JK100-F | 200 µg | 143.00 USD | |
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Brain (rat), (tissue extract) |
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| Rat brain extract, WB | Print as PDF | ||||||
| ADI-LYT-RB100-F | 200 µg | 225.00 USD | |
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