| ADI-905-308-100 | 100 µg | 484.00 USD |  |
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| Alternative Name: | Interleukin-21 receptor, IL-21 receptor, CD360 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human IL-21R precursor. |
| UniProt ID: | Q9HBE5 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (10µg/ml) Western Blot (0.5-1.0µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~60kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | IL-21 is a cytokine identified in human and mouse that shows significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R) also termed NILR for novel interleukin receptor) is a member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling via the JAK-Stat pathway. IL-21 is expressed in activated T-cells, as well as HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B- and T-cell populations. |
| Regulatory Status: | RUO - Research Use Only |
