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IL-31 (human), (recombinant)

 
ENZ-PRT261-0100 100 µg 1,420.00 USD
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Product Specification

Alternative Name:Interleukin-31
 
MW:Monomer, 15.8 kDa (141 amino acids)
 
Source:Produced in E.coli.
 
UniProt ID:Q6EBC2
 
Formulation:Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg
 
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR). IL-31 promotes allergic reactions and inflammatory skin diseases.
 
ENZ-PRT261 WB
Figure 1: Human IL-31 induced activation of STAT in U-87MG cells.
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ENZ-PRT261 WB

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