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United States 

IL-17A (human), (recombinant)

 
ENZ-PRT188-0025 25 µg 202.00 USD
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Product Specification

Alternative Name:Interleukin-17, CTLA8, Cytotoxic T-lymphocyte-associated serine esterase 8
 
MW:~31.3 kDa
 
Source:Produced in E. coli.
 
UniProt ID:Q16552
 
Formulation:Lyophilized with no additives.
 
Purity:≥98% (SDS & HPLC)
 
Purity Detail:Sterile filtered through a 0.2 micron filter.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-20°C
 
Scientific Background:IL-17A is produced as a disulfide-linked homodimer that can also form heterodimers with IL-17F. IL-17 acts via ubiquitously expressed IL-17 receptors, inducing expression of pro-inflammatory factors such as IL-1, IL-6, TNF, CXCL8/IL-8, and matrix metalloproteinases. Elevated levels of IL-17A and increased presence of Th17 cells has been associated with airway inflammation, rheumatoid arthritis, intraperitoneal abscesses, inflammatory bowel disease, allograft rejection, psoriasis, multiple sclerosis, and cancer.
 

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